Healthcare groups drug makers, device companies, insurers, and care providers under one industry-group label — not a single product cycle and not the same as a biotech index. Combined size is not a sector return. See how the ranking works.
351 U.S.-listed Healthcare companies with a market cap of at least $1B are ranked here by market capitalization, worth a combined $9.73T — 10.35% of the total market tracked on MarketCapLens. The most valuable is Eli Lilly and Company at $1.27T. As of November 6, 2026. Size ranking for research, not a sector recommendation.
| Industry | Companies | Combined cap | % of sector |
|---|---|---|---|
| Drug Manufacturers - General | 16 | $4.6T | 47.28% |
| Biotechnology | 154 | $1.24T | 12.69% |
| Medical - Diagnostics & Research | 27 | $913.24B | 9.38% |
| Medical - Devices | 39 | $819.93B | 8.42% |
| Medical - Healthcare Plans | 11 | $743.13B | 7.63% |
| Medical - Instruments & Supplies | 24 | $430.62B |
The largest company, Eli Lilly and Company (LLY), is 13.09% of Healthcare. The three largest — Eli Lilly and Company (LLY), Johnson & Johnson (JNJ), and AbbVie Inc. (ABBV) — are 25.20% of the sector. The ten largest are 46.01%. Eli Lilly and Company is classified as Drug Manufacturers - General, which is also the largest industry in this sector by combined cap.
| Weight |
|---|
| 301 | Ultragenyx Pharmaceutical Inc.RARE | $1.52B | $15.43 | -0.90% | 4.05M | 0.02% |
| 302 | uniQure N.V.QURE | $1.51B | $21.70 | +3.28% | 1.17M | 0.02% |
| 303 | U.S. Physical Therapy, Inc.USPH | $1.48B | $99.49 | +2.36% | 295.07K | 0.02% |
| 304 | ADARx Pharmaceuticals, Inc.ADRX | $1.47B | $13.23 | -0.45% | 439.98K | 0.02% |
| 305 | Damora Therapeutics, Inc.DMRA | $1.46B | $23.70 | +8.42% | 360.45K | 0.02% |
| 306 | Nuvation Bio Inc.NUVB | $1.46B | $4.16 | -0.72% | 5.33M | 0.02% |
| 307 | Pacira BioSciences, Inc.PCRX | $1.45B | $36.43 | +0.03% | 537.09K | 0.01% |
| 308 | Ocular Therapeutix, Inc.OCUL | $1.45B | $6.60 | +2.57% | 1.96M | 0.01% |
| 309 | Ascentage Pharma Group InternationalAAPG | $1.43B | $15.43 | +1.98% | 5.54K | 0.01% |
| 310 | Taysha Gene Therapies, Inc.TSHA | $1.41B | $4.33 | +5.87% | 3.18M | 0.01% |
| 311 | AMN Healthcare Services, Inc.AMN | $1.4B | $36.19 | -23.68% | 1.86M | 0.01% |
| 312 | AnaptysBio, Inc.ANAB | $1.39B | $46.45 | +1.91% | 287.66K | 0.01% |
| 313 | Kardigan, Inc.KARD | $1.39B | $15.52 | +11.98% | 406.39K | 0.01% |
| 314 | Innoviva, Inc.INVA | $1.38B | $19.10 | -0.73% | 1.65M | 0.01% |
| 315 | Mineralys Therapeutics, Inc.MLYS | $1.36B | $15.33 | +0.59% | 1.34M | 0.01% |
| 316 | LB Pharmaceuticals Inc Common StockLBRX | $1.36B | $42.01 | +10.29% | 476.19K | 0.01% |
| 317 | Phibro Animal Health CorporationPAHC | $1.34B | $32.96 | -6.89% | 283.55K | 0.01% |
| 318 | Cronos Group Inc.CRON | $1.33B | $3.61 | -2.96% | 1.29M | 0.01% |
| 319 | Avalyn Pharma Inc. Common StockAVLN | $1.29B | $29.15 | +9.30% | 630.26K | 0.01% |
| 320 | OPKO Health, Inc.OPK | $1.29B | $1.73 | -1.14% | 6.89M | 0.01% |
| 321 | Lumexa Imaging Holdings, Inc. Common StockLMRI | $1.29B | $13.43 | +1.67% | 322.86K | 0.01% |
| 322 | GH Research PLCGHRS | $1.28B | $18.61 | +0.92% | 453.63K | 0.01% |
| 323 | The Pennant Group, Inc.PNTG | $1.27B | $36.36 | -9.10% | 1.12M | 0.01% |
| 324 | Alpha Tau Medical LtdDRTS | $1.27B | $13.72 | +3.16% | 417.32K | 0.01% |
| 325 | STAAR Surgical CompanySTAA | $1.26B | $25.21 | -5.65% | 1.04M | 0.01% |
| 326 | Tyra Biosciences, Inc.TYRA | $1.26B | $21.15 | +1.24% | 862.26K | 0.01% |
| 327 | MannKind CorporationMNKD | $1.25B | $3.90 | +3.72% | 4.98M | 0.01% |
| 328 | Inhibrx Biosciences Inc.INBX | $1.24B | $84.52 | +5.28% | 220.14K | 0.01% |
| 329 | Nutex Health, Inc.NUTX | $1.24B | $180.56 | -6.75% | 167.92K | 0.01% |
| 330 | SpyGlass Pharma, Inc. Common StockSGP | $1.24B | $36.95 | +8.41% | 109.37K | 0.01% |
| 331 | Omeros CorporationOMER | $1.22B | $16.92 | -0.88% | 1.01M | 0.01% |
| 332 | Innovage Holding Corp.INNV | $1.22B | $8.97 | -1.32% | 750.3K | 0.01% |
| 333 | COMPASS Pathways plcCMPS | $1.22B | $8.61 | +10.24% | 3.75M | 0.01% |
| 334 | Amphastar Pharmaceuticals, Inc.AMPH | $1.21B | $28.49 | +3.00% | 826.25K | 0.01% |
| 335 | UroGen Pharma Ltd.URGN | $1.21B | $24.75 | -3.81% | 1.74M | 0.01% |
| 336 | GoodRx Holdings, Inc.GDRX | $1.2B | $3.51 | +0.57% | 1.17M | 0.01% |
| 337 | PROCEPT BioRobotics CorporationPRCT | $1.18B | $20.62 | +1.73% | 1.71M | 0.01% |
| 338 | Tandem Diabetes Care, Inc.TNDM | $1.18B | $16.91 | -6.00% | 5.88M | 0.01% |
| 339 | Rapport Therapeutics, Inc. Common StockRAPP | $1.17B | $24.44 | +3.04% | 866.41K | 0.01% |
| 340 | Structure Therapeutics Inc.GPCR | $1.17B | $20.35 | +6.66% | 1.62M | 0.01% |
| 341 | Alphatec Holdings, Inc.ATEC | $1.15B | $7.44 | -4.62% | 3.16M | 0.01% |
| 342 | Akso Health GroupAHG | $1.15B | $1.35 | +4.25% | 13.33K | 0.01% |
| 343 | Seaport Therapeutics, Inc. Common StockSPTX | $1.15B | $21.50 | +5.44% | 227.03K | 0.01% |
| 344 | IRadimed CorporationIRMD | $1.1B | $86.31 | +0.90% | 167.25K | 0.01% |
| 345 | SI-BONE, Inc.SIBN | $1.09B | $24.24 | -0.12% | 683.47K | 0.01% |
| 346 | Janux Therapeutics, Inc.JANX | $1.08B | $17.63 | +9.78% | 852.23K | 0.01% |
| 347 | Vor Biopharma Inc.VOR | $1.08B | $19.88 | +6.54% | 550.77K | 0.01% |
| 348 | Nektar TherapeuticsNKTR | $1.07B | $37.26 | +3.07% | 608K | 0.01% |
| 349 | Integra LifeSciences Holdings CorporationIART | $1.04B | $13.42 | -4.96% | 871.88K | 0.01% |
| 350 | CeriBell, Inc.CBLL | $1.03B | $26.59 | +2.23% | 436.39K | 0.01% |
| 351 | Harrow Health, Inc.HROW | $1.01B | $26.89 | +3.26% | 650.06K | 0.01% |
| 4.42% |
| Drug Manufacturers - Specialty & Generic | 24 | $283.15B | 2.91% |
|---|
| Medical - Distribution | 5 | $261B | 2.68% |
|---|
| Other | 51 | $445.51B | 4.58% |
|---|
Read the industry rows as labeled: drug manufacturers, medical devices, diagnostics, managed care, and providers sit side by side. Combined market cap is equity size, not a health-care return, and it is not a pipeline score.